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Gena Health, rare cancer care platform

A safety-first AI foundation for rare cancer care

Gena Health operates a specialised rare cancer care platform serving patients with orphan diseases and complex oncological conditions. Moterra delivered a Rapid AI Assessment for a conversational, evidence-based patient and clinician experience - where medical accuracy, safety and compliance were the non-negotiables.

Client Gena Health Sector Healthcare technology - rare cancer care Scale HIPAA-compliant platform for patients, oncologists and care coordinators Solution AI Consulting - Rapid AI Assessment
What they got
Three models tested On medical reasoning Claude 4 Sonnet, Nova Pro and Nova Lite compared on medical accuracy, clinical reasoning, safety features and patient-communication quality against real rare cancer scenarios.
Working sandbox From day one Conversational patient education, clinical trials matching and care-coordinator decision support prototyped inside Moterra Business AI Suite.
Healthcare-grade RAG HIPAA, safety, clinical trust Amazon Bedrock with OpenSearch vector search, Orphanet and clinical-trials integration, HIPAA-aligned handling, and mandatory clinician oversight on every output.
01

The situation

Gena Health serves patients with rare cancers - a population facing significant barriers accessing specialised medical information, complex treatment protocols and clinical trials. Existing static information delivery falls short of what these patients and their care coordinators actually need: personalised, evidence-based, safe answers, available around the clock, with a clinician always in the loop.

02

What they needed

An evidence-based view with patient safety as the non-negotiable starting point.

Which foundation model actually performs on medical reasoning and rare cancer scenarios?How do we deliver accurate, empathetic conversational experiences while keeping clinicians in control?What does a HIPAA-aligned RAG architecture look like on AWS, integrating Orphanet, clinical trials data and internal knowledge?How do we build in the safety, disclaimers and audit trails that patients, clinicians and regulators expect?
03

What Moterra delivered

A Rapid AI Assessment scoped to Gena Health’s context, with safety treated as a design constraint rather than a review step.

Stakeholder and readiness workEngagement with product, clinical and compliance leaders, plus an organisational AI readiness review.
Use case prioritisationConversational patient education, clinical trials matching, care-pathway guidance and clinician decision support.
Comparative model benchmarkingOn medical reasoning tasks, with particular attention to accuracy, safety features, uncertainty expression and communication quality.
Data readiness reviewAcross Orphanet, clinical trials repositories, genomic resources and internal patient education content.
Healthcare-grade RAG architectureAmazon Bedrock, OpenSearch vector search, HIPAA-aligned data handling and audit-trail compliance on AWS.
Risk matrix with human-in-the-loopClinical safety, model hallucination, regulatory adherence and clinician adoption - with mandatory clinician review across every use case.

Throughout the engagement, Gena Health had access to Moterra Business AI Suite as a working sandbox, used to prototype and validate the core use cases against representative clinical data.

04

The outcome

Gena Health’s leadership got a safety-first AI plan - model choice grounded in medical accuracy and safety, a HIPAA-aligned RAG architecture, a phased path to production, and a governance model built on clinician oversight - the kind of foundation patients, oncologists and regulators expect for rare cancer care.

Uncertainty as a feature

In most sectors, a model expressing uncertainty is a weakness. In rare cancer care it is a safety requirement - which is why it was a benchmark criterion, not a footnote.

Questions

Frequently asked questions

What problem did Gena Health need to solve?

Gena Health serves patients with rare cancers - a population facing significant barriers accessing specialised medical information, complex treatment protocols and clinical trials. Existing static information delivery falls short of what these patients and their care coordinators actually need: personalised, evidence-based, safe answers, available around the clock, with a clinician always in the loop.

What did Moterra deploy for Gena Health?

A Rapid AI Assessment scoped to Gena Health’s context, with safety treated as a design constraint rather than a review step.

What results did Gena Health see?

Gena Health’s leadership got a safety-first AI plan - model choice grounded in medical accuracy and safety, a HIPAA-aligned RAG architecture, a phased path to production, and a governance model built on clinician oversight - the kind of foundation patients, oncologists and regulators expect for rare cancer care.

Where does the deployment run?

Inside the client’s own cloud tenant, in the region they choose. The deployment is Private Claude Cowork by Moterra, with admin, MDM and governance handled by Moterra AI Bridge. Moterra builds in AWS and Azure, operates as a data processor under a DPA covering UK and EU GDPR, and the stack is ISO 27001 and ISO 42001 certified across the AWS and Anthropic layers.

How long does a deployment like this take?

Standard deployment is typically live within one to two weeks, covering environment and region setup, the identity path from your SSO, managed configuration through your MDM, and the connector allowlist.

Read the deployment behind this story: Private Claude Cowork by Moterra for the environment itself, and Moterra AI Bridge for the admin, MDM, plugin and agent layer around it.

Amanda Uzialaite Written by Amanda Uzialaite CMO at Moterra. More about the team.
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Moterra Claude Partner Network - Select Services Partner

Moterra is a private AI deployment company and a Select Services Partner in the Claude Partner Network. We help businesses deploy Claude inside their own AWS or Azure environment, connect it to the tools they already use, and keep it secure and governed, so everyday processes get faster.

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Build your Private Claude Cowork plan. Pick users, support, and MCP plugins. We show the monthly cost, Year 1 TCO, and how it compares to Enterprise editions of Claude, ChatGPT and M365 Copilot. Get this quote straight to your inbox when you are done.
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02 Support Standard is included in every plan.
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03 MCP plugins Optional. 4 or more get 20% off the plugin total.
04 Commitment A term waives the one-time setup fee.
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Indicative figures. Moterra includes private deployment in your own AWS; others are shared-cloud SaaS. Final quote confirmed in writing by your Moterra account manager.

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